6SND

crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide

6SND の概要

• エントリーDOI: 10.2210/pdb6snd/pdb
• 分子名称: LN01 light chain, LN01 heavy chain, Envelope glycoprotein gp160, ... (7 entities in total)
• 機能のキーワード: gp41, antibody, complex, mper, immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 105520.13

構造登録者

Caillat, C.,Pinto, D.,Corti, D.,Fenwick, C.,Pantaleo, G.,Weissenhorn, W. (登録日: 2019-08-23, 公開日: 2019-11-06, 最終更新日: 2020-07-29)

• 主引用文献: Pinto, D.,Fenwick, C.,Caillat, C.,Silacci, C.,Guseva, S.,Dehez, F.,Chipot, C.,Barbieri, S.,Minola, A.,Jarrossay, D.,Tomaras, G.D.,Shen, X.,Riva, A.,Tarkowski, M.,Schwartz, O.,Bruel, T.,Dufloo, J.,Seaman, M.S.,Montefiori, D.C.,Lanzavecchia, A.,Corti, D.,Pantaleo, G.,Weissenhorn, W.; Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.; Cell Host Microbe, 26:623-637.e8, 2019; PubMed: 31653484; DOI: 10.1016/j.chom.2019.09.016

実験手法

X-RAY DIFFRACTION (3.1 Å)