6SKQ

OXA-655_MEM. Structural insights into the enhanced carbapenemase efficiency of OXA-655 compared to OXA-10.

Summary for 6SKQ

• Entry DOI: 10.2210/pdb6skq/pdb
• Related: 6SKP
• Descriptor: Beta-lactamase, (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, SULFATE ION, ... (4 entities in total)
• Functional Keywords: class d beta-lactamase, crystal structures, carbapenemases, antibiotic resistance, antibiotic
• Biological source: Escherichia coli
• Total number of polymer chains: 4
• Total formula weight: 120525.57

Authors

Leiros, H.-K.S. (deposition date: 2019-08-16, release date: 2019-09-18, Last modification date: 2024-01-24)

• Primary citation: Leiros, H.S.,Thomassen, A.M.,Samuelsen, O.,Flach, C.F.,Kotsakis, S.D.,Larsson, D.G.J.; Structural insights into the enhanced carbapenemase efficiency of OXA-655 compared to OXA-10.; Febs Open Bio, 10:1821-1832, 2020; PubMed: 32683794; DOI: 10.1002/2211-5463.12935

Experimental method

X-RAY DIFFRACTION (2.1 Å)