6SKP
OXA-10_IPM. Structural insight to the enhanced carbapenem efficiency of OXA-655 compared to OXA-10.
Summary for 6SKP
Entry DOI | 10.2210/pdb6skp/pdb |
Descriptor | Beta-lactamase, (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, SODIUM ION, ... (5 entities in total) |
Functional Keywords | class d beta-lactamase, crystal structures, carbapenemases, antibiotic resistance, antibiotic |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 59939.33 |
Authors | Leiros, H.-K.S. (deposition date: 2019-08-16, release date: 2019-09-18, Last modification date: 2024-01-24) |
Primary citation | Leiros, H.S.,Thomassen, A.M.,Samuelsen, O.,Flach, C.F.,Kotsakis, S.D.,Larsson, D.G.J. Structural insights into the enhanced carbapenemase efficiency of OXA-655 compared to OXA-10. Febs Open Bio, 10:1821-1832, 2020 Cited by PubMed: 32683794DOI: 10.1002/2211-5463.12935 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.891 Å) |
Structure validation
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