6SAM

Structure of human butyrylcholinesterase in complex with 1-(2,3-dihydro-1H-inden2-yl)piperidin-3-yl N-phenyl carbamate

6SAM の概要

• エントリーDOI: 10.2210/pdb6sam/pdb
• 分子名称: Cholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: butyrylcholinesterase, inhibitor, complex, carbamate, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 63026.79

構造登録者

Brazzolotto, X.,Kosak, U.,Strasek, N.,Knez, D.,Gobec, S.,Nachon, F. (登録日: 2019-07-17, 公開日: 2020-04-29, 最終更新日: 2024-01-24)

• 主引用文献: Kosak, U.,Strasek, N.,Knez, D.,Jukic, M.,Zakelj, S.,Zahirovic, A.,Pislar, A.,Brazzolotto, X.,Nachon, F.,Kos, J.,Gobec, S.; N-alkylpiperidine carbamates as potential anti-Alzheimer's agents.; Eur.J.Med.Chem., 197:112282-112282, 2020; PubMed: 32380361; DOI: 10.1016/j.ejmech.2020.112282

実験手法

X-RAY DIFFRACTION (2.5 Å)