6S50

scdSav(SARK)mv2 - Engineering Single-Chain Dimeric Streptavidin as Host for Artificial Metalloenzymes

Summary for 6S50

Entry DOI	10.2210/pdb6s50/pdb
Descriptor	Streptavidin, {N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(chloro)[(1,2,3,4,5-eta)-1,2,3,4,5-pentamethylcyclopentadienyl]iridium(III), GLYCEROL, ... (5 entities in total)
Functional Keywords	biotin-binding protein, artificial transfer hydrogenase, beta barrel, streptavidin, transport protein
Biological source	Streptomyces avidinii More
Total number of polymer chains	2
Total formula weight	73802.24
Authors	Rebelein, J.G. (deposition date: 2019-06-29, release date: 2019-09-25, Last modification date: 2024-01-24)
Primary citation	Wu, S.,Zhou, Y.,Rebelein, J.G.,Kuhn, M.,Mallin, H.,Zhao, J.,Igareta, N.V.,Ward, T.R. Breaking Symmetry: Engineering Single-Chain Dimeric Streptavidin as Host for Artificial Metalloenzymes. J.Am.Chem.Soc., 141:15869-15878, 2019 Cited by PubMed: 31509711 DOI: 10.1021/jacs.9b06923 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation