6S2T

Structure of the N-terminal catalytic region of T. thermophilus Rel bound to ppGpp

Summary for 6S2T

Entry DOI	10.2210/pdb6s2t/pdb
Descriptor	(P)ppGpp synthetase I, SpoT/RelA, GUANOSINE-5',3'-TETRAPHOSPHATE, GLYCEROL, ... (8 entities in total)
Functional Keywords	ppgpp hydrolase, ppgpp synthetase, rel, ppgpp, transferase
Biological source	Thermus thermophilus
Total number of polymer chains	1
Total formula weight	41630.92
Authors	Garcia-Pino, A. (deposition date: 2019-06-22, release date: 2020-07-08, Last modification date: 2024-01-24)
Primary citation	Tamman, H.,Van Nerom, K.,Takada, H.,Vandenberk, N.,Scholl, D.,Polikanov, Y.,Hofkens, J.,Talavera, A.,Hauryliuk, V.,Hendrix, J.,Garcia-Pino, A. A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes. Nat.Chem.Biol., 16:834-840, 2020 Cited by PubMed: 32393900 DOI: 10.1038/s41589-020-0520-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation