6RXR
Crystal structure of CobB Ac2 (A76G, I131C, V162G) in complex with H4K16Cr-2'OH-ADPr peptide intermediate after co-crystallisation
Summary for 6RXR
Entry DOI | 10.2210/pdb6rxr/pdb |
Descriptor | NAD-dependent protein deacylase, Histone H4, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{S})-4-[(~{E})-but-2-enoxy]-3,5-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate, ... (4 entities in total) |
Functional Keywords | deacylase, nad-dependent, hydrolase |
Biological source | Escherichia coli (strain K12) More |
Total number of polymer chains | 8 |
Total formula weight | 119750.59 |
Authors | Spinck, M.,Gasper, R.,Neumann, H. (deposition date: 2019-06-08, release date: 2020-04-15, Last modification date: 2024-01-24) |
Primary citation | Spinck, M.,Neumann-Staubitz, P.,Ecke, M.,Gasper, R.,Neumann, H. Evolved, Selective Erasers of Distinct Lysine Acylations. Angew.Chem.Int.Ed.Engl., 59:11142-11149, 2020 Cited by PubMed: 32187803DOI: 10.1002/anie.202002899 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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