6RU0

Light-Regulation of Imidazole Glycerol Phosphate Synthase by Interference with its Allosteric Machinery through Photo-Sensitive Unnatural Amino Acids

Summary for 6RU0

Entry DOI	10.2210/pdb6ru0/pdb
Descriptor	Imidazole glycerol phosphate synthase subunit HisF, Imidazole glycerol phosphate synthase subunit HisH, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	unnatural amino acids, phenylalanine-4'-azobenzene (azof), o-nitropiperonyl-o-tyrosine (npy), lyase
Biological source	Thermotoga maritima More
Total number of polymer chains	6
Total formula weight	153118.51
Authors	Kneuttinger, A.,Rajendran, C.,Sterner, R. (deposition date: 2019-05-27, release date: 2020-05-20, Last modification date: 2024-05-15)
Primary citation	Kneuttinger, A.C.,Straub, K.,Bittner, P.,Simeth, N.A.,Bruckmann, A.,Busch, F.,Rajendran, C.,Hupfeld, E.,Wysocki, V.H.,Horinek, D.,Konig, B.,Merkl, R.,Sterner, R. Light Regulation of Enzyme Allostery through Photo-responsive Unnatural Amino Acids. Cell Chem Biol, 26:1501-1514.e9, 2019 Cited by PubMed: 31495713 DOI: 10.1016/j.chembiol.2019.08.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.648 Å)

Structure validation