6RU0

Light-Regulation of Imidazole Glycerol Phosphate Synthase by Interference with its Allosteric Machinery through Photo-Sensitive Unnatural Amino Acids

6RU0 の概要

• エントリーDOI: 10.2210/pdb6ru0/pdb
• 分子名称: Imidazole glycerol phosphate synthase subunit HisF, Imidazole glycerol phosphate synthase subunit HisH, PHOSPHATE ION, ... (4 entities in total)
• 機能のキーワード: unnatural amino acids, phenylalanine-4'-azobenzene (azof), o-nitropiperonyl-o-tyrosine (npy), lyase
• 由来する生物種: Thermotoga maritima; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 153118.51

構造登録者

Kneuttinger, A.,Rajendran, C.,Sterner, R. (登録日: 2019-05-27, 公開日: 2020-05-20, 最終更新日: 2024-05-15)

• 主引用文献: Kneuttinger, A.C.,Straub, K.,Bittner, P.,Simeth, N.A.,Bruckmann, A.,Busch, F.,Rajendran, C.,Hupfeld, E.,Wysocki, V.H.,Horinek, D.,Konig, B.,Merkl, R.,Sterner, R.; Light Regulation of Enzyme Allostery through Photo-responsive Unnatural Amino Acids.; Cell Chem Biol, 26:1501-1514.e9, 2019; PubMed: 31495713; DOI: 10.1016/j.chembiol.2019.08.006

実験手法

X-RAY DIFFRACTION (2.648 Å)