6RTZ
Light-Regulation of Imidazole Glycerol Phosphate Synthase by Interference with its Allosteric Machinery through Photo-Sensitive Unnatural Amino Acids
Summary for 6RTZ
Entry DOI | 10.2210/pdb6rtz/pdb |
Descriptor | Imidazole glycerol phosphate synthase subunit HisF, Imidazole glycerol phosphate synthase subunit HisH, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | unnatural amino acids, phenylalanine-4'-azobenzene (azof), o-nitropiperonyl-o-tyrosine (npy), lyase |
Biological source | Thermotoga maritima More |
Total number of polymer chains | 2 |
Total formula weight | 51074.38 |
Authors | Kneuttinger, A.,Rajendran, C.,Sterner, R. (deposition date: 2019-05-27, release date: 2020-05-20, Last modification date: 2024-01-24) |
Primary citation | Kneuttinger, A.C.,Straub, K.,Bittner, P.,Simeth, N.A.,Bruckmann, A.,Busch, F.,Rajendran, C.,Hupfeld, E.,Wysocki, V.H.,Horinek, D.,Konig, B.,Merkl, R.,Sterner, R. Light Regulation of Enzyme Allostery through Photo-responsive Unnatural Amino Acids. Cell Chem Biol, 26:1501-1514.e9, 2019 Cited by PubMed: 31495713DOI: 10.1016/j.chembiol.2019.08.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.87 Å) |
Structure validation
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