6RRP

Crystal structure of tyrosinase PvdP from Pseudomonas aeruginosa bound to copper and phenylthiourea

Summary for 6RRP

Entry DOI	10.2210/pdb6rrp/pdb
Descriptor	PvdP, N-PHENYLTHIOUREA, COPPER (II) ION, ... (4 entities in total)
Functional Keywords	tyrosinase, pyoverdine, copper, inhibitor, phenylthiourea, oxidoreductase
Biological source	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Total number of polymer chains	2
Total formula weight	125322.83
Authors	Wibowo, J.P.,Batista, F.A.,van Oosterwijk, N.,Groves, M.R.,Dekker, F.J.,Quax, W.J. (deposition date: 2019-05-20, release date: 2020-04-15, Last modification date: 2024-01-24)
Primary citation	Wibowo, J.P.,Batista, F.A.,van Oosterwijk, N.,Groves, M.R.,Dekker, F.J.,Quax, W.J. A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa. Int.J.Biol.Macromol., 146:212-221, 2020 Cited by PubMed: 31899238 DOI: 10.1016/j.ijbiomac.2019.12.252 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation