6RPA

Crystal structure of the T-cell receptor NYE_S2 bound to HLA A2*01-SLLMWITQV

6RPA の概要

• エントリーDOI: 10.2210/pdb6rpa/pdb
• 分子名称: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Heteroclitic NY-ESO-1 157-165 peptide, ... (6 entities in total)
• 機能のキーワード: t-cell receptor, peptide-human leukocyte antigen complex, ny-eso-1, cancer testis antigen, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 95867.60

構造登録者

Coles, C.H.,Mulvaney, R.,Malla, S.,Lloyd, A.,Smith, K.,Chester, F.,Knox, A.,Stacey, A.R.,Dukes, J.,Baston, E.,Griffin, S.,Vuidepot, A.,Jakobsen, B.K.,Harper, S. (登録日: 2019-05-14, 公開日: 2020-01-15, 最終更新日: 2024-01-24)

• 主引用文献: Coles, C.H.,Mulvaney, R.M.,Malla, S.,Walker, A.,Smith, K.J.,Lloyd, A.,Lowe, K.L.,McCully, M.L.,Martinez Hague, R.,Aleksic, M.,Harper, J.,Paston, S.J.,Donnellan, Z.,Chester, F.,Wiederhold, K.,Robinson, R.A.,Knox, A.,Stacey, A.R.,Dukes, J.,Baston, E.,Griffin, S.,Jakobsen, B.K.,Vuidepot, A.,Harper, S.; TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex.; J Immunol., 204:1943-1953, 2020; PubMed: 32102902; DOI: 10.4049/jimmunol.1900915

実験手法

X-RAY DIFFRACTION (2.56 Å)