6RN9
DPP1 in complex with inhibitor
Summary for 6RN9
Entry DOI | 10.2210/pdb6rn9/pdb |
Descriptor | Dipeptidyl peptidase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
Functional Keywords | dipeptidyl peptidase i, inhibitor complex, cathepsin c, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 41195.65 |
Authors | Kack, H. (deposition date: 2019-05-08, release date: 2019-08-28, Last modification date: 2024-01-24) |
Primary citation | Kack, H.,Doyle, K.,Hughes, S.J.,Bodnarchuk, M.S.,Lonn, H.,Van De Poel, A.,Palmer, N. DPP1 Inhibitors: Exploring the Role of Water in the S2 Pocket of DPP1 with Substituted Pyrrolidines. Acs Med.Chem.Lett., 10:1222-1227, 2019 Cited by PubMed: 31413809DOI: 10.1021/acsmedchemlett.9b00261 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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