6RJ8

Structure of the alpha-beta hydrolase CorS from Tabernathe iboga

Summary for 6RJ8

Entry DOI	10.2210/pdb6rj8/pdb
Descriptor	alpha-beta hydrolase CorS, TETRAETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywords	alkaloid, iboga, coronaridine, natural product, biosynthesis, alpha/beta hydrolase fold, hydrolase
Biological source	Tabernanthe iboga
Total number of polymer chains	1
Total formula weight	37284.17
Authors	Farrow, S.C.,Caputi, L.,Kamileen, M.O.,Bussey, K.,Stevenson, C.E.M.,Mundy, J.,Lawson, D.M.,O'Connor, S.E. (deposition date: 2019-04-26, release date: 2020-03-04, Last modification date: 2024-01-24)
Primary citation	Caputi, L.,Franke, J.,Bussey, K.,Farrow, S.C.,Vieira, I.J.C.,Stevenson, C.E.M.,Lawson, D.M.,O'Connor, S.E. Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids. Nat.Chem.Biol., 16:383-386, 2020 Cited by PubMed: 32066966 DOI: 10.1038/s41589-019-0460-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.42 Å)

Structure validation