6R94

Cryo-EM structure of NCP_THF2(-3)

Summary for 6R94

• Entry DOI: 10.2210/pdb6r94/pdb
• EMDB information: 4768
• Descriptor: Human alpha-satellite DNA (145-MER), Human alpha-satellite DNA (145-MER) with abasic sites at positions 97-98, Histone H3.1, ... (6 entities in total)
• Functional Keywords: dna damage, nucleosome, 6-4 photoproduct, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 201332.06

Authors

Matsumoto, S.,Cavadini, S.,Bunker, R.D.,Thoma, N.H. (deposition date: 2019-04-02, release date: 2019-06-12, Last modification date: 2019-12-18)

• Primary citation: Matsumoto, S.,Cavadini, S.,Bunker, R.D.,Grand, R.S.,Potenza, A.,Rabl, J.,Yamamoto, J.,Schenk, A.D.,Schubeler, D.,Iwai, S.,Sugasawa, K.,Kurumizaka, H.,Thoma, N.H.; DNA damage detection in nucleosomes involves DNA register shifting.; Nature, 571:79-84, 2019; PubMed: 31142837; DOI: 10.1038/s41586-019-1259-3

Experimental method

ELECTRON MICROSCOPY (3.5 Å)