6R6V
Structure of recombinant human butyrylcholinesterase in complex with a fluorescent coumarin-based probe
Summary for 6R6V
Entry DOI | 10.2210/pdb6r6v/pdb |
Descriptor | Cholinesterase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | butyrylcholinesterase, protein-ligand complex, fluorescent probe, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 62562.39 |
Authors | Brazzolotto, X.,Nachon, F.,Knez, D.,Gobec, S. (deposition date: 2019-03-28, release date: 2020-01-15, Last modification date: 2024-01-24) |
Primary citation | Pajk, S.,Knez, D.,Kosak, U.,Zorovic, M.,Brazzolotto, X.,Coquelle, N.,Nachon, F.,Colletier, J.P.,Zivin, M.,Stojan, J.,Gobec, S. Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes. J Enzyme Inhib Med Chem, 35:498-505, 2020 Cited by PubMed: 31914836DOI: 10.1080/14756366.2019.1710502 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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