6R6T

Crystal structure of mouse cis-aconitate decarboxylase

6R6T の概要

• エントリーDOI: 10.2210/pdb6r6t/pdb
• 分子名称: Cis-aconitate decarboxylase (2 entities in total)
• 機能のキーワード: immunity, inflammatory response, innate immunity, antimicrobial, decarboxylase, cis-aconitate, itaconate, lyase
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 115743.17

構造登録者

Lukat, P.,Chen, F.,Saile, K.,Buessow, K.,Pessler, F.,Blankenfeldt, W. (登録日: 2019-03-28, 公開日: 2019-09-25, 最終更新日: 2024-01-24)

• 主引用文献: Chen, F.,Lukat, P.,Iqbal, A.A.,Saile, K.,Kaever, V.,van den Heuvel, J.,Blankenfeldt, W.,Bussow, K.,Pessler, F.; Crystal structure ofcis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis.; Proc.Natl.Acad.Sci.USA, 116:20644-20654, 2019; PubMed: 31548418; DOI: 10.1073/pnas.1908770116

実験手法

X-RAY DIFFRACTION (2.535 Å)