6R5K

Cryo-EM structure of a poly(A) RNP bound to the Pan2-Pan3 deadenylase

Summary for 6R5K

Entry DOI	10.2210/pdb6r5k/pdb
EMDB information	4728
Descriptor	PAN2-PAN3 deadenylation complex catalytic subunit PAN2, Polyadenylate-binding protein, cytoplasmic and nuclear, poly(A) RNA, ... (6 entities in total)
Functional Keywords	poly(a)-tail, mrna, rnp, pabp, pab1, pan2-pan3, ccr4-not, deadenylase, rrm, cryoem, rna binding protein
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More
Total number of polymer chains	7
Total formula weight	482279.15
Authors	Schaefer, I.B.,Conti, E. (deposition date: 2019-03-25, release date: 2019-05-29, Last modification date: 2024-05-15)
Primary citation	Schafer, I.B.,Yamashita, M.,Schuller, J.M.,Schussler, S.,Reichelt, P.,Strauss, M.,Conti, E. Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase. Cell, 177:1619-, 2019 Cited by PubMed: 31104843 DOI: 10.1016/j.cell.2019.04.013 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.8 Å)

Structure validation