6R5A

Crystal structure of PPEP-1(W103F)

Summary for 6R5A

DescriptorPro-Pro endopeptidase, ZINC ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywordspro-pro endopeptidase 1, zinc metallopeptidase, clostridium difficile, virulence factor, hydrolase
Biological sourcePeptoclostridium difficile
Total number of polymer chains2
Total molecular weight44264.4
Authors
Pichlo, C.,Baumann, U. (deposition date: 2019-03-24, release date: 2019-06-12, Last modification date: 2019-08-07)
Primary citation
Pichlo, C.,Juetten, L.,Wojtalla, F.,Schacherl, M.,Diaz, D.,Baumann, U.
Molecular determinants of the mechanism and substrate specificity ofClostridium difficileproline-proline endopeptidase-1.
J.Biol.Chem., 294:11525-11535, 2019
PubMed: 31182482 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.RA119.009029
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.48 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.19910 0.3% 1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report