6R36
T. brucei farnesyl pyrophosphate synthase (FPPS)
Summary for 6R36
| Entry DOI | 10.2210/pdb6r36/pdb |
| Descriptor | Farnesyl pyrophosphate synthase, DIMETHYL SULFOXIDE, DI(HYDROXYETHYL)ETHER, ... (4 entities in total) |
| Functional Keywords | sterol biosynthesis, farnesyl diphosphate synthase, trypanosoma brucei, homodimer, transferase |
| Biological source | Trypanosoma brucei |
| Total number of polymer chains | 1 |
| Total formula weight | 42431.60 |
| Authors | Muenzker, L.,Petrick, J.K.,Schleberger, C.,Jahnke, W. (deposition date: 2019-03-19, release date: 2020-04-08, Last modification date: 2024-01-24) |
| Primary citation | Munzker, L.,Petrick, J.K.,Schleberger, C.,Clavel, D.,Cornaciu, I.,Wilcken, R.,Marquez, J.A.,Klebe, G.,Marzinzik, A.,Jahnke, W. Fragment-Based Discovery of Non-bisphosphonate Binders of Trypanosoma brucei Farnesyl Pyrophosphate Synthase. Chembiochem, 21:3096-3111, 2020 Cited by PubMed: 32537808DOI: 10.1002/cbic.202000246 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
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