6R2C
Crystal structure of the SucA domain of Mycobacterium smegmatis KGD after soaking with succinylphosphonate phosphonoethyl ester (PESP)
Summary for 6R2C
Entry DOI | 10.2210/pdb6r2c/pdb |
Descriptor | Multifunctional 2-oxoglutarate metabolism enzyme, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | oxoglutarate dehydrogenase, tpp-dependent decarboxylase, oxidoreductase |
Biological source | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) |
Total number of polymer chains | 4 |
Total formula weight | 391465.87 |
Authors | Wagner, T.,Alzari, P.M.,Bellinzoni, M. (deposition date: 2019-03-15, release date: 2019-09-11, Last modification date: 2024-01-24) |
Primary citation | Wagner, T.,Boyko, A.,Alzari, P.M.,Bunik, V.I.,Bellinzoni, M. Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts. J.Struct.Biol., 208:182-190, 2019 Cited by PubMed: 31476368DOI: 10.1016/j.jsb.2019.08.012 PDB entries with the same primary citation |
Experimental method |
Structure validation
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