6R2C

Crystal structure of the SucA domain of Mycobacterium smegmatis KGD after soaking with succinylphosphonate phosphonoethyl ester (PESP)

6R2C の概要

• エントリーDOI: 10.2210/pdb6r2c/pdb
• 分子名称: Multifunctional 2-oxoglutarate metabolism enzyme, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: oxoglutarate dehydrogenase, tpp-dependent decarboxylase, oxidoreductase
• 由来する生物種: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 391465.87

構造登録者

Wagner, T.,Alzari, P.M.,Bellinzoni, M. (登録日: 2019-03-15, 公開日: 2019-09-11, 最終更新日: 2024-01-24)

• 主引用文献: Wagner, T.,Boyko, A.,Alzari, P.M.,Bunik, V.I.,Bellinzoni, M.; Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts.; J.Struct.Biol., 208:182-190, 2019; PubMed: 31476368; DOI: 10.1016/j.jsb.2019.08.012

実験手法