6R25

Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 3

Summary for 6R25

Entry DOI	10.2210/pdb6r25/pdb
EMDB information	4710
Descriptor	Lysine-specific histone demethylase 1B, FLAVIN-ADENINE DINUCLEOTIDE, ZINC ION, ... (12 entities in total)
Functional Keywords	histone demethylation, chromatin reader, flavoenzyme, epigenetics, evolution of protein function, molecular recognition., gene regulation
Biological source	Homo sapiens (Human) More
Total number of polymer chains	13
Total formula weight	304538.97
Authors	Marabelli, C.,Pilotto, S.,Chittori, S.,Subramaniam, S.,Mattevi, A. (deposition date: 2019-03-15, release date: 2019-04-24)
Primary citation	Marabelli, C.,Marrocco, B.,Pilotto, S.,Chittori, S.,Picaud, S.,Marchese, S.,Ciossani, G.,Forneris, F.,Filippakopoulos, P.,Schoehn, G.,Rhodes, D.,Subramaniam, S.,Mattevi, A. A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27:387-399.e7, 2019 Cited by PubMed: 30970244 DOI: 10.1016/j.celrep.2019.03.061 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.61 Å)

Structure validation