6R25
Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 3
Summary for 6R25
Entry DOI | 10.2210/pdb6r25/pdb |
EMDB information | 4710 |
Descriptor | Lysine-specific histone demethylase 1B, FLAVIN-ADENINE DINUCLEOTIDE, ZINC ION, ... (12 entities in total) |
Functional Keywords | histone demethylation, chromatin reader, flavoenzyme, epigenetics, evolution of protein function, molecular recognition., gene regulation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 13 |
Total formula weight | 304538.97 |
Authors | Marabelli, C.,Pilotto, S.,Chittori, S.,Subramaniam, S.,Mattevi, A. (deposition date: 2019-03-15, release date: 2019-04-24) |
Primary citation | Marabelli, C.,Marrocco, B.,Pilotto, S.,Chittori, S.,Picaud, S.,Marchese, S.,Ciossani, G.,Forneris, F.,Filippakopoulos, P.,Schoehn, G.,Rhodes, D.,Subramaniam, S.,Mattevi, A. A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27:387-399.e7, 2019 Cited by PubMed: 30970244DOI: 10.1016/j.celrep.2019.03.061 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.61 Å) |
Structure validation
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