6R25

Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 3

6R25 の概要

• エントリーDOI: 10.2210/pdb6r25/pdb
• EMDBエントリー: 4710
• 分子名称: Lysine-specific histone demethylase 1B, FLAVIN-ADENINE DINUCLEOTIDE, ZINC ION, ... (12 entities in total)
• 機能のキーワード: histone demethylation, chromatin reader, flavoenzyme, epigenetics, evolution of protein function, molecular recognition., gene regulation
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 13
• 化学式量合計: 304538.97

構造登録者

Marabelli, C.,Pilotto, S.,Chittori, S.,Subramaniam, S.,Mattevi, A. (登録日: 2019-03-15, 公開日: 2019-04-24)

• 主引用文献: Marabelli, C.,Marrocco, B.,Pilotto, S.,Chittori, S.,Picaud, S.,Marchese, S.,Ciossani, G.,Forneris, F.,Filippakopoulos, P.,Schoehn, G.,Rhodes, D.,Subramaniam, S.,Mattevi, A.; A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.; Cell Rep, 27:387-399.e7, 2019; PubMed: 30970244; DOI: 10.1016/j.celrep.2019.03.061

実験手法

ELECTRON MICROSCOPY (4.61 Å)