6R0I

Glycogen Phosphorylase b in complex with 4

6R0I の概要

• エントリーDOI: 10.2210/pdb6r0i/pdb
• 分子名称: Glycogen phosphorylase, muscle form, ~{N}-[(2~{R},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-4-phenyl-benzamide, PYRIDOXAL-5'-PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: transferase
• 由来する生物種: Oryctolagus cuniculus (Rabbit)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 98028.91

構造登録者

Koulas, M.S.,Tsagkarakou, S.A.,Kyriakis, E.,Stravodimos, G.A.,Skamnaki, V.T.,Leonidas, D.D. (登録日: 2019-03-13, 公開日: 2019-04-17, 最終更新日: 2019-04-24)

• 主引用文献: Fischer, T.,Koulas, S.M.,Tsagkarakou, A.S.,Kyriakis, E.,Stravodimos, G.A.,Skamnaki, V.T.,Liggri, P.G.V.,Zographos, S.E.,Riedl, R.,Leonidas, D.D.; High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-beta-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors.; Molecules, 24:-, 2019; PubMed: 30987252; DOI: 10.3390/molecules24071322

実験手法

X-RAY DIFFRACTION (2.4 Å)