6R07
T. cruzi FPPS in complex with 2-(5-chlorobenzo[b]thiophen-3-yl)acetic acid
Summary for 6R07
Entry DOI | 10.2210/pdb6r07/pdb |
Descriptor | Farnesyl diphosphate synthase, (5-chloro-1-benzothiophen-3-yl)acetic acid, ZINC ION, ... (6 entities in total) |
Functional Keywords | farnesyl diphosphate synthase, sterol biosynthesis, farnesyl pyrophosphate, homodimer, transferase |
Biological source | Trypanosoma cruzi |
Total number of polymer chains | 1 |
Total formula weight | 42117.95 |
Authors | Petrick, J.K.,Muenzker, L.,Schleberger, C.,Jahnke, W. (deposition date: 2019-03-12, release date: 2020-04-01, Last modification date: 2024-02-07) |
Primary citation | Petrick, J.K.,Jahnke, W. Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery Thesis, 2019 Cited by DOI: 10.17192/z2019.0501PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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