6R06

T. CRUZI FPPS IN COMPLEX WITH (3S,4S)-4-(3,4-dimethylphenoxy)-1-(prop-2-yn-1-yl)piperidin-3-ol

6R06 の概要

• エントリーDOI: 10.2210/pdb6r06/pdb
• 分子名称: Farnesyl diphosphate synthase, (3~{S},4~{S})-4-(3,4-dimethylphenoxy)-1-prop-2-ynyl-piperidin-3-ol, ZINC ION, ... (6 entities in total)
• 機能のキーワード: farnesyl diphosphate synthase, sterol biosynthesis, farnesyl pyrophosphate, homodimer, transferase
• 由来する生物種: Trypanosoma cruzi
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42260.25

構造登録者

Petrick, J.K.,Muenzker, L.,Schleberger, C.,Wolfgang, J. (登録日: 2019-03-12, 公開日: 2020-04-01, 最終更新日: 2024-02-07)

• 主引用文献: Petrick, J.K.,Jahnke, W.; Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery; Thesis, 2019; DOI: 10.17192/z2019.0501

実験手法

X-RAY DIFFRACTION (1.559 Å)