6QW8
Crystal structure of CTX-M-15 complexed with relebactam (16 hour soak)
Summary for 6QW8
Entry DOI | 10.2210/pdb6qw8/pdb |
Descriptor | Beta-lactamase, (2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy)amino]piperidine-2-carboxamide, SULFATE ION, ... (5 entities in total) |
Functional Keywords | inhibitor, relebactam, diazabicyclooctane, antibiotic resistance., antimicrobial protein |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 29023.66 |
Authors | Tooke, C.L.,Hinchliffe, P.,Spencer, J. (deposition date: 2019-03-05, release date: 2019-08-21, Last modification date: 2024-01-24) |
Primary citation | Tooke, C.L.,Hinchliffe, P.,Lang, P.A.,Mulholland, A.J.,Brem, J.,Schofield, C.J.,Spencer, J. Molecular Basis of Class A beta-Lactamase Inhibition by Relebactam. Antimicrob.Agents Chemother., 63:-, 2019 Cited by PubMed: 31383664DOI: 10.1128/AAC.00564-19 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.1 Å) |
Structure validation
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