6QSH

Crystal structure of the hybrid bioinorganic complex of Pizza6S linked by the 1:2 Ce-substituted Keggin

6QSH の概要

• エントリーDOI: 10.2210/pdb6qsh/pdb
• 分子名称: Pizza6S, 1:2 Ce-substituted Keggin (3 entities in total)
• 機能のキーワード: artificial beta-propeller protein, de novo protein, computational design, polyoxometalate, pom, pizza, polyoxometalate-protein framework, pom-protein framework, 1:2 ce-substituted keggin
• 由来する生物種: Synthetic construct
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36712.32

構造登録者

Noguchi, H.,Vandebroek, L.,Kamata, K.,Tame, J.R.H.,Van Meervelt, L.,Parac-Vogt, T.N.,Voet, A.R.D. (登録日: 2019-02-20, 公開日: 2020-03-18, 最終更新日: 2024-01-24)

主引用文献

Vandebroek, L.,Noguchi, H.,Kamata, K.,Tame, J.R.H.,Van Meervelt, L.,Parac-Vogt, T.N.,Voet, A.R.D.
Hybrid assemblies of a symmetric designer protein and polyoxometalates with matching symmetry.
Chem.Commun.(Camb.), 56:11601-11604, 2020

PubMed Abstract: Novel bioinorganic hybrid materials based on proteins and inorganic clusters have enormous potential for the development of hybrid catalysts that synergistically combine properties of both materials. Here we report the creation of hybrid assemblies between a computationally designed symmetrical protein Pizza6-S and different polyoxometalates with matching symmetry: the tellurotungstic Anderson-Evans (Na6[TeW6O24]·22H2O) (TEW); Keggin (H4[SiW12O40]·6H2O) (STA); and 1 : 2 CeIII-substituted Keggin (K11[CeIII[PW11O39]2]·20H2O) (Ce-K). This results in the formation of complexes with clearly defined stoichiometries in solution. Crystal structures validate the complexes as building blocks for the formation of larger assemblies.

PubMed: 32869783
DOI: 10.1039/d0cc05071g

実験手法

X-RAY DIFFRACTION (2.5 Å)