6QSC

Crystal Structure of Arg470His mutant of Human Prolidase with Mn ions and GlyPro ligand

Summary for 6QSC

• Entry DOI: 10.2210/pdb6qsc/pdb
• Related: 5M4G 5M4J 5MBZ
• Descriptor: Xaa-Pro dipeptidase, MANGANESE (II) ION, MANGANESE ION, 1 HYDROXYL COORDINATED, ... (7 entities in total)
• Functional Keywords: hydrolase, metal binding, dipeptidase, mutation
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 110655.00

Authors

Wilk, P.,Wator, E.,Weiss, M.S. (deposition date: 2019-02-20, release date: 2020-03-18, Last modification date: 2024-03-06)

• Primary citation: Linhares, N.D.,Wilk, P.,Wator, E.,Tostes, M.A.,Weiss, M.S.,Pena, S.D.J.; Structural analysis of new compound heterozygous variants in PEPD gene identified in a patient with Prolidase Deficiency diagnosed by exome sequencing.; Genet Mol Biol, 44:e20200393-e20200393, 2021; PubMed: 33877262; DOI: 10.1590/1678-4685-GMB-2020-0393

Experimental method

X-RAY DIFFRACTION (1.569 Å)