6QS1

Crystal structure of human Angiotensin-1 converting enzyme N-domain in complex with BPPb

6QS1 の概要

• エントリーDOI: 10.2210/pdb6qs1/pdb
• 分子名称: Angiotensin-converting enzyme, BORIC ACID, TRIETHYLENE GLYCOL, ... (16 entities in total)
• 機能のキーワード: angiotensin-1 converting enzyme, ace inhibitor, bradykinin potentiating peptide, vasopeptidase inhibitor, hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 152628.27

構造登録者

Cozier, G.E.,Acharya, K.R. (登録日: 2019-02-20, 公開日: 2019-05-22, 最終更新日: 2024-01-24)

• 主引用文献: Sturrock, E.D.,Lubbe, L.,Cozier, G.E.,Schwager, S.L.U.,Arowolo, A.T.,Arendse, L.B.,Belcher, E.,Acharya, K.R.; Structural basis for the C-domain-selective angiotensin-converting enzyme inhibition by bradykinin-potentiating peptide b (BPPb).; Biochem.J., 476:1553-1570, 2019; PubMed: 31072910; DOI: 10.1042/BCJ20190290

実験手法

X-RAY DIFFRACTION (1.8 Å)