6QRO

Crystal structure of Tannerella forsythia glutaminyl cyclase

Summary for 6QRO

Entry DOI	10.2210/pdb6qro/pdb
Related	6QQL
Descriptor	Glutamine cyclotransferase, ZINC ION, SULFATE ION, ... (4 entities in total)
Functional Keywords	pyroglutamate formation, glutaminyl-peptide cyclotransferase, globular alpha/beta-hydrolase fold, zinc ion, transferase
Biological source	Tannerella forsythia (strain ATCC 43037 / JCM 10827 / FDC 338) (Bacteroides forsythus)
Total number of polymer chains	4
Total formula weight	143675.44
Authors	Linnert, M.,Piechotta, A.,Parthier, C.,Taudte, N.,Kolenko, P.,Rahfeld, J.,Potempa, J.,Stubbs, M.T. (deposition date: 2019-02-19, release date: 2019-03-06, Last modification date: 2024-01-24)
Primary citation	Taudte, N.,Linnert, M.,Rahfeld, J.U.,Piechotta, A.,Ramsbeck, D.,Buchholz, M.,Kolenko, P.,Parthier, C.,Houston, J.A.,Veillard, F.,Eick, S.,Potempa, J.,Schilling, S.,Demuth, H.U.,Stubbs, M.T. Mammalian-like type II glutaminyl cyclases in Porphyromonas gingivalis and other oral pathogenic bacteria as targets for treatment of periodontitis. J.Biol.Chem., 296:100263-100263, 2021 Cited by PubMed: 33837744 DOI: 10.1016/j.jbc.2021.100263 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation