6QP1

Crystal structure of the PLP-bound C-S lyase in the external aldimine form from Staphylococcus hominis complexed with an inhibitor, L-cycloserine.

6QP1 の概要

• エントリーDOI: 10.2210/pdb6qp1/pdb
• 関連するPDBエントリー: 6QP2 6QP3 6RVI 6RVJ
• 分子名称: Aminotransferase, [5-hydroxy-6-methyl-4-({[(4E)-3-oxo-1,2-oxazolidin-4-ylidene]amino}methyl)pyridin-3-yl]methyl dihydrogen phosphate (3 entities in total)
• 機能のキーワード: pyridoxal phosphate binding, cystathionine beta-lyase, lyase, inhibitor, complex, l-cycloserine, external aldimine
• 由来する生物種: Staphylococcus hominis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 97519.74

構造登録者

Herman, R.,Rudden, M.,Wilkinson, A.J.,Hanai, S.,Thomas, G.H. (登録日: 2019-02-13, 公開日: 2020-03-04, 最終更新日: 2024-01-24)

• 主引用文献: Rudden, M.,Herman, R.,Rose, M.,Bawdon, D.,Cox, D.S.,Dodson, E.,Holden, M.T.G.,Wilkinson, A.J.,James, A.G.,Thomas, G.H.; The molecular basis of thioalcohol production in human body odour.; Sci Rep, 10:12500-12500, 2020; PubMed: 32719469; DOI: 10.1038/s41598-020-68860-z

実験手法

X-RAY DIFFRACTION (1.42 Å)