6QLQ

Galectin-3C in complex with fluoroaryltriazole monothiogalactoside derivative 4

6QLQ の概要

• エントリーDOI: 10.2210/pdb6qlq/pdb
• 分子名称: Galectin-3, DI(HYDROXYETHYL)ETHER, (2~{R},3~{R},4~{S},5~{R},6~{S})-4-[4-(4-fluorophenyl)-1,2,3-triazol-1-yl]-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-oxane-3,5-diol, ... (5 entities in total)
• 機能のキーワード: lectin, carbohydrate-binding protein, galactose-specific lectin 3, galactoside-binding protein, galbp, ige-6 binding protein, l-31, laminin-binding protein, lectin l-29, mac-2, sugar binding protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16274.10

構造登録者

Kumar, R.,Peterson, K.,Nilsson, U.J.,Logan, D.T. (登録日: 2019-02-01, 公開日: 2019-07-10, 最終更新日: 2024-01-24)

• 主引用文献: Kumar, R.,Ignjatovic, M.M.,Peterson, K.,Olsson, M.,Leffler, H.,Ryde, U.,Nilsson, U.J.,Logan, D.T.; Structure and Energetics of Ligand-Fluorine Interactions with Galectin-3 Backbone and Side-Chain Amides: Insight into Solvation Effects and Multipolar Interactions.; Chemmedchem, 14:1528-1536, 2019; PubMed: 31246331; DOI: 10.1002/cmdc.201900293

実験手法

X-RAY DIFFRACTION (1.079 Å)