The crystal structure of Pol2CORE in complex with DNA and an incoming nucleotide, carrying an Fe-S cluster

Summary for 6QIB

DescriptorDNA polymerase epsilon catalytic subunit A, Primer_11ddC, Template16, ... (6 entities in total)
Functional Keywordspol epsilon, dna, complex, dna binding protein, fe-s, p-domain
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains3
Total molecular weight146252.21
Parkash, V.,Johansson, E. (deposition date: 2019-01-18, release date: 2019-04-17, Last modification date: 2019-04-24)
Primary citation
Ter Beek, J.,Parkash, V.,Bylund, G.O.,Osterman, P.,Sauer-Eriksson, A.E.,Johansson, E.
Structural evidence for an essential Fe-S cluster in the catalytic core domain of DNA polymerase ε.
Nucleic Acids Res., 2019
PubMed: 30968138 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gkz248
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.28619 0.2% 5.1% 0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6qib
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Molmil generated image of 6qib
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Molmil generated image of 6qib
rotated about y axis by 90°