6QH7

AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation

6QH7 の概要

• エントリーDOI: 10.2210/pdb6qh7/pdb
• 分子名称: AP-2 complex subunit alpha, AP-2 complex subunit beta, ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ... (6 entities in total)
• 機能のキーワード: endocytosis, phosphorylation, cell membrane, protein transport
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 257983.91

構造登録者

Wrobel, A.G.,Owen, D.J.,McCoy, A.J.,Evans, P.R. (登録日: 2019-01-15, 公開日: 2019-09-04)

• 主引用文献: Wrobel, A.G.,Kadlecova, Z.,Kamenicky, J.,Yang, J.C.,Herrmann, T.,Kelly, B.T.,McCoy, A.J.,Evans, P.R.,Martin, S.,Muller, S.,Sroubek, F.,Neuhaus, D.,Honing, S.,Owen, D.J.; Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.; Dev.Cell, 50:494-508.e11, 2019; PubMed: 31430451; DOI: 10.1016/j.devcel.2019.07.017

実験手法

X-RAY DIFFRACTION (3.4 Å)