6QFV

Human carbonic anhydrase II with bound IrCp* complex (cofactor 8) to generate an artificial transfer hydrogenase (ATHase)

6QFV の概要

• エントリーDOI: 10.2210/pdb6qfv/pdb
• 分子名称: Carbonic anhydrase 2, 4-[2-(9-chloranyl-2',3',4',5',6'-pentamethyl-7-oxidanylidene-spiro[1$l^{4},8-diaza-9$l^{8}-iridabicyclo[4.3.0]nona-1(6),2,4-triene-9,1'-1$l^{8}-iridapentacyclo[2.2.0.0^{1,3}.0^{1,5}.0^{2,6}]hexane]-8-yl)ethyl]benzenesulfonamide, ZINC ION, ... (5 entities in total)
• 機能のキーワード: artificial transfer hydrogenase, bound ircp* complex, zinc binding protein, human carbonic anhydrase ii, oxidoreductase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30197.84

構造登録者

Rebelein, J.G. (登録日: 2019-01-10, 公開日: 2019-04-17, 最終更新日: 2024-01-24)

• 主引用文献: Rebelein, J.G.,Cotelle, Y.,Garabedian, B.,Ward, T.R.; Chemical Optimization of Whole-Cell Transfer Hydrogenation Using Carbonic Anhydrase as Host Protein.; Acs Catalysis, 9:4173-4178, 2019; PubMed: 31080690; DOI: 10.1021/acscatal.9b01006

実験手法

X-RAY DIFFRACTION (1.45 Å)