6QE6

Structure of M. capricolum TrmK in complex with the natural cofactor product S-adenosyl-homocysteine (SAH)

6QE6 の概要

• エントリーDOI: 10.2210/pdb6qe6/pdb
• 分子名称: tRNA (Adenine(22)-N(1))-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
• 機能のキーワード: rna mtases, methyltransferase, m6a, transition state analogue, inhibitor, rna binding, trmk, rlmj, m1a, structure., transferase
• 由来する生物種: Mycoplasma capricolum subsp. capricolum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 57789.97

構造登録者

Oerum, S.,Catala, M.,Atdjian, C.,Brachet, F.,Ponchon, L.,Barraud, P.,Iannazzo, L.,Droogmans, L.,Braud, E.,Etheve-Quelquejeu, M.,Tisne, C. (登録日: 2019-01-04, 公開日: 2019-03-27, 最終更新日: 2024-01-24)

• 主引用文献: Oerum, S.,Catala, M.,Atdjian, C.,Brachet, F.,Ponchon, L.,Barraud, P.,Iannazzo, L.,Droogmans, L.,Braud, E.,Etheve-Quelquejeu, M.,Tisne, C.; Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.; Rna Biol., 16:798-808, 2019; PubMed: 30879411; DOI: 10.1080/15476286.2019.1589360

実験手法

X-RAY DIFFRACTION (2.36 Å)