6QAH

ERK2 mini-fragment binding

Summary for 6QAH

Entry DOI	10.2210/pdb6qah/pdb
Descriptor	Mitogen-activated protein kinase 1, SULFATE ION, 1-azanylpropylideneazanium, ... (4 entities in total)
Functional Keywords	ser/thr kinase, signal transduction, atp binding, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	42794.22
Authors	O'Reilly, M.,Cleasby, A.,Davies, T.G.,Hall, R.,Ludlow, F.,Murray, C.W.,Tisi, D.,Jhoti, H. (deposition date: 2018-12-19, release date: 2019-06-26)
Primary citation	O'Reilly, M.,Cleasby, A.,Davies, T.G.,Hall, R.J.,Ludlow, R.F.,Murray, C.W.,Tisi, D.,Jhoti, H. Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design. Drug Discov Today, 24:1081-1086, 2019 Cited by PubMed: 30878562 DOI: 10.1016/j.drudis.2019.03.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation