Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6QAE

Human Butyrylcholinesterase in complex with (S)-N2-butyl-N1-(2-cycloheptylethyl)-3-(1H-indol-3-yl)-N1,N2-dimethylpropane-1,2-diamine

6QAE の概要
エントリーDOI10.2210/pdb6qae/pdb
分子名称Cholinesterase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
機能のキーワードbutyrylcholinesterase, inhibitor, complex, hydrolase
由来する生物種Homo sapiens (Human)
タンパク質・核酸の鎖数1
化学式量合計66081.70
構造登録者
Brazzolotto, X.,Nachon, F.,Harst, M.,Knez, D.,Gobec, S. (登録日: 2018-12-19, 公開日: 2019-03-27, 最終更新日: 2024-01-24)
主引用文献Meden, A.,Knez, D.,Jukic, M.,Brazzolotto, X.,Grsic, M.,Pislar, A.,Zahirovic, A.,Kos, J.,Nachon, F.,Svete, J.,Gobec, S.,Groselj, U.
Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease.
Chem.Commun.(Camb.), 55:3765-3768, 2019
Cited by
PubMed: 30864579
DOI: 10.1039/c9cc01330j
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (2.487 Å)
構造検証レポート
Validation report summary of 6qae
検証レポート(詳細版)ダウンロードをダウンロード

222415

件を2024-07-10に公開中

PDB statisticsPDBj update infoContact PDBjnumon