6QAD

Human Butyrylcholinesterase in complex with ((S)-2-(butylamino)-N-(2-(4-(dimethylamino)cyclohexyl)ethyl)-3-(1H-indol-3-yl)propanamide

6QAD の概要

• エントリーDOI: 10.2210/pdb6qad/pdb
• 分子名称: Cholinesterase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: butyrylcholinesterase, inhibitor, complex, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 66640.33

構造登録者

Brazzolotto, X.,Nachon, F.,Harst, M.,Knez, D.,Gobec, S. (登録日: 2018-12-19, 公開日: 2019-03-27, 最終更新日: 2024-01-24)

• 主引用文献: Meden, A.,Knez, D.,Jukic, M.,Brazzolotto, X.,Grsic, M.,Pislar, A.,Zahirovic, A.,Kos, J.,Nachon, F.,Svete, J.,Gobec, S.,Groselj, U.; Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease.; Chem.Commun.(Camb.), 55:3765-3768, 2019; PubMed: 30864579; DOI: 10.1039/c9cc01330j

実験手法

X-RAY DIFFRACTION (2.497 Å)