Crystal structure of a de novo designed antiparallel four-helix coiled coil apCC-Tet

Summary for 6Q5S

DescriptorapCC-Tet (2 entities in total)
Functional Keywordscoiled coil, synthetic, antiparallel, tetramer, de novo protein
Biological sourcesynthetic construct
Total number of polymer chains4
Total molecular weight12939.48
Beesley, J.L.,Guto, G.R.,Wood, C.W.,Brady, R.L.,Woolfson, D.N. (deposition date: 2018-12-09, release date: 2019-05-22, Last modification date: 2019-06-19)
Primary citation
Rhys, G.G.,Wood, C.W.,Beesley, J.L.,Zaccai, N.R.,Burton, A.J.,Brady, R.L.,Thomson, A.R.,Woolfson, D.N.
Navigating the Structural Landscape of De Novo alpha-Helical Bundles.
J.Am.Chem.Soc., 141:8787-8797, 2019
PubMed: 31066556 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.8b13354
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23270 1.2%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution