Crystal structure of a CC-Hex mutant that forms an antiparallel four-helix coiled coil CC-Hex*-LL-KgEb

Summary for 6Q5R

DescriptorCC-Hex*-LL-KgEb, GLYCEROL (3 entities in total)
Functional Keywordscoiled coil, tetramer, synthetic, antiparallel, cc-hex, de novo protein
Biological sourcesynthetic construct
Total number of polymer chains12
Total molecular weight39002.64
Beesley, J.L.,Rhys, G.G.,Wood, C.W.,Brady, R.L.,Woolfson, D.N. (deposition date: 2018-12-09, release date: 2019-05-22)
Primary citation
Rhys, G.G.,Wood, C.W.,Beesley, J.L.,Zaccai, N.R.,Burton, A.,Brady, R.L.,Thomson, A.R.,Woolfson, D.N.
Navigating the structural landscape of de novo alpha-helical bundles.
J.Am.Chem.Soc., 2019
PubMed: 31066556 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.8b13354
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.239100 2.1% 2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6q5r
no rotation
Molmil generated image of 6q5r
rotated about x axis by 90°
Molmil generated image of 6q5r
rotated about y axis by 90°