6Q1Z

Crystal structure of human 1G04 Fab in complex with influenza virus neuraminidase from A/Hunan/02650/2016 (H7N9)

Summary for 6Q1Z

• Entry DOI: 10.2210/pdb6q1z/pdb
• Descriptor: Neuraminidase, 1G04 Fab kappa light chain, 1G04 Fab IgG1 heavy chain, ... (7 entities in total)
• Functional Keywords: broadly protective human antibody, neuraminidase, inhibition, active site, antibody-neuraminidase complex, viral protein, hydrolase-immune system complex, hydrolase/immune system
• Biological source: Influenza A virus; More
• Total number of polymer chains: 6
• Total formula weight: 192775.46

Authors

Zhu, X.,Wilson, I.A. (deposition date: 2019-08-06, release date: 2019-10-23, Last modification date: 2023-10-11)

• Primary citation: Stadlbauer, D.,Zhu, X.,McMahon, M.,Turner, J.S.,Wohlbold, T.J.,Schmitz, A.J.,Strohmeier, S.,Yu, W.,Nachbagauer, R.,Mudd, P.A.,Wilson, I.A.,Ellebedy, A.H.,Krammer, F.; Broadly protective human antibodies that target the active site of influenza virus neuraminidase.; Science, 366:499-504, 2019; PubMed: 31649200; DOI: 10.1126/science.aay0678

Experimental method

X-RAY DIFFRACTION (3.446 Å)