6Q0J
Structure of a MAPK pathway complex
Summary for 6Q0J
Entry DOI | 10.2210/pdb6q0j/pdb |
EMDB information | 20550 |
Descriptor | Serine/threonine-protein kinase B-raf, Dual specificity mitogen-activated protein kinase kinase 1, 14-3-3 protein zeta, ... (6 entities in total) |
Functional Keywords | transferase, transferase-protein binding complex, transferase/protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 328707.26 |
Authors | Park, E.,Rawson, S.,Jeon, H.,Eck, M.J. (deposition date: 2019-08-01, release date: 2019-10-09, Last modification date: 2020-04-22) |
Primary citation | Park, E.,Rawson, S.,Li, K.,Kim, B.W.,Ficarro, S.B.,Pino, G.G.,Sharif, H.,Marto, J.A.,Jeon, H.,Eck, M.J. Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature, 575:545-550, 2019 Cited by PubMed: 31581174DOI: 10.1038/s41586-019-1660-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.9 Å) |
Structure validation
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