6PYA

Sex Hormone-binding globulin mutant E176K in complex with IPI

Summary for 6PYA

Entry DOI	10.2210/pdb6pya/pdb
Descriptor	Sex hormone-binding globulin, 3-[(1H-imidazol-1-yl)methyl]-2-phenyl-1H-indole, CALCIUM ION, ... (4 entities in total)
Functional Keywords	sex steroid transport binding globulin, hormone
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	22924.10
Authors	Round, P.W.,Das, S.,Van Petegem, F. (deposition date: 2019-07-29, release date: 2019-12-25, Last modification date: 2020-02-12)
Primary citation	Round, P.,Das, S.,Wu, T.S.,Wahala, K.,Van Petegem, F.,Hammond, G.L. Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity. J.Biol.Chem., 295:1202-1211, 2020 Cited by PubMed: 31852737 DOI: 10.1074/jbc.RA119.011051 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.71 Å)

Structure validation