6PXR

Anti-TAU BIIB092 FAB with TAU peptide

Summary for 6PXR

• Entry DOI: 10.2210/pdb6pxr/pdb
• Descriptor: gosuranemab Fab, light chain, gosuranemab Fab, heavy chain, Microtubule-associated protein tau, ... (4 entities in total)
• Functional Keywords: tau, antibody, biib092, gosuranemab tau complex, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 48772.42

Authors

Arndt, J.W.,Quan, C. (deposition date: 2019-07-26, release date: 2020-07-29, Last modification date: 2021-02-10)

• Primary citation: Sopko, R.,Golonzhka, O.,Arndt, J.,Quan, C.,Czerkowicz, J.,Cameron, A.,Smith, B.,Murugesan, Y.,Gibbons, G.,Kim, S.J.,Trojanowski, J.Q.,Lee, V.M.Y.,Brunden, K.R.,Graham, D.L.,Weinreb, P.H.,Hering, H.; Characterization of tau binding by gosuranemab.; Neurobiol.Dis., 146:105120-105120, 2020; PubMed: 32991997; DOI: 10.1016/j.nbd.2020.105120

Experimental method

X-RAY DIFFRACTION (1.556 Å)