6PTU

Crystal Structure of Class D Beta-lactamase OXA-48 with Imipenem

Summary for 6PTU

Entry DOI	10.2210/pdb6ptu/pdb
Descriptor	Class D Carbapenemase OXA-48, CHLORIDE ION, Imipenem, ... (4 entities in total)
Functional Keywords	carbapenemase, carbapenem, substrate, hydrolyzed product, hydrolase
Biological source	Klebsiella pneumoniae
Total number of polymer chains	4
Total formula weight	124725.69
Authors	Akhtar, A.,Chen, Y. (deposition date: 2019-07-16, release date: 2020-01-22, Last modification date: 2023-10-11)
Primary citation	Akhtar, A.,Pemberton, O.A.,Chen, Y. Structural Basis for Substrate Specificity and Carbapenemase Activity of OXA-48 Class D beta-Lactamase. Acs Infect Dis., 6:261-271, 2020 Cited by PubMed: 31872762 DOI: 10.1021/acsinfecdis.9b00304 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.004 Å)

Structure validation