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6PSG

Crystal Structure of Class D Beta-lactamase OXA-48 with Faropenem

Summary for 6PSG
Entry DOI10.2210/pdb6psg/pdb
DescriptorClass D Carbapenemase OXA-48, CHLORIDE ION, (2R,5R)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-5-[(2R)-tetrahydrofuran-2-yl]-2,5-dihydro-1,3-thiazole-4-carboxylic acid, ... (5 entities in total)
Functional Keywordscarbapenemase, carbapenem, substrate, hydrolyzed product, hydrolase
Biological sourceKlebsiella pneumoniae
Total number of polymer chains4
Total formula weight124619.85
Authors
Akhtar, A.,Chen, Y. (deposition date: 2019-07-12, release date: 2020-01-22, Last modification date: 2023-10-11)
Primary citationAkhtar, A.,Pemberton, O.A.,Chen, Y.
Structural Basis for Substrate Specificity and Carbapenemase Activity of OXA-48 Class D beta-Lactamase.
Acs Infect Dis., 6:261-271, 2020
Cited by
PubMed: 31872762
DOI: 10.1021/acsinfecdis.9b00304
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.13 Å)
Structure validation

221051

數據於2024-06-12公開中

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