6PQA
GAVVGG segment 119-124 from human prion
Summary for 6PQA
Entry DOI | 10.2210/pdb6pqa/pdb |
Related | 6PQ5 |
Descriptor | Major prion protein (2 entities in total) |
Functional Keywords | amyloid-like protofibril, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 458.51 |
Authors | Apostol, M.I.,Sawaya, M.R.,Eisenberg, D. (deposition date: 2019-07-08, release date: 2020-04-15, Last modification date: 2024-03-13) |
Primary citation | Glynn, C.,Sawaya, M.R.,Ge, P.,Gallagher-Jones, M.,Short, C.W.,Bowman, R.,Apostol, M.,Zhou, Z.H.,Eisenberg, D.S.,Rodriguez, J.A. Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core. Nat.Struct.Mol.Biol., 27:417-423, 2020 Cited by PubMed: 32284600DOI: 10.1038/s41594-020-0403-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.46 Å) |
Structure validation
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